Patent · US Active

Multiepitope vaccine cassettes

US11771747B2 · kind B2 · utility

0Cited by

103References

23Claims

0Family size

Assignee

Gritstone Bio, Inc. · US

Inventors

Karin Jooss · Emeryville, US
Roman Yelensky · Newton, US
James Xin Sun · Cambridge, US
Amy Rachel Rappaport · Daly City, US
Ciaran Daniel Scallan · San Francisco, US
Leonid Gitlin · Foster City, US
Christine Denise Palmer · Cambridge, US
Monica Lane · Uxbridge, US

Key dates

Filing date	Apr 22, 2022
Grant date	Oct 3, 2023
Priority date	—
Expiry date	Apr 22, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2830/50
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are compositions that include antigen-encoding nucleic acid sequences having multiple iterations of KRAS neoepitope-encoding sequences and/or lacking immunodominant epitopes. Also disclosed are nucleotides, cells, and methods associated with the compositions including their use as vaccines.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.