3′ protected nucleotides

US11773130B2 · kind B2 · utility

Assignee

• Roche Sequencing Solutions, Inc. · US

Inventors

• Frank Bergmann · Iffeldorf, DE
• Peter Crisalli · Mountain View, US
• Dieter Heindl · Munich, DE
• Omid Khakshoor · Lathrop, US
• Meng Taing · San Mateo, US

Key dates

• Filing date: Jul 6, 2022
• Grant date: Oct 3, 2023
• Expiry date: Jul 6, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/6869
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present disclosure provides 3′ protected nucleotides, including those 3′ protected nucleotides having a detectable tag. Systems and methods of sequencing nucleic acids using the 3′ protected nucleotides are also disclosed, such as the sequencing of a nucleic acid using a nanopore or the sequencing of a nucleic acid via sequencing-by-synthesis.