High-affinity human ACE2 construct for use in diagnosing and treating coronaviruses
US11773385B2 · kind B2 · utility
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Key dates
| Filing date | May 19, 2021 |
| Grant date | Oct 3, 2023 |
| Priority date | — |
| Expiry date | Mar 16, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2469/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein, in some aspects, are polypeptide monomers comprising an angiotensin-converting enzyme 2 (ACE2) ectodomain and an oligomerization domain. Also provided herein are oligomeric complexes comprising ACE2 monomers. Methods of using such to monomers and oligomeric complexes for the diagnosis, prevention, and treatment of viral infections such as the coronavirus are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.