bZIP transcription factors regulate conversion of nicotine to nornicotine
US11773401B2 · kind B2 · utility
1Cited by
1References
8Claims
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Key dates
| Filing date | Dec 6, 2018 |
| Grant date | Oct 3, 2023 |
| Priority date | — |
| Expiry date | Mar 6, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3231
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of decreasing conversion of nicotine to nornicotine is provided herein. The methods includes administering at least one basic region/leucine zipper (bZIP) type transcription factor inhibitor to an organism in need thereof. Also provided herein is a method of decreasing conversion of nicotine to nornicotine including mutating a bZIP type transcription factor binding site on a promoter of a nicotine N-demethylase (NND). Further provided herein is a method of decreasing conversion of nicotine to nornicotine including mutating a plant genome to knockout at least one bZIP type transcription factor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.