Method of discovering specific functional antibodies
US11773510B2 · kind B2 · utility
0Cited by
3References
14Claims
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Inventors
Key dates
| Filing date | May 24, 2017 |
| Grant date | Oct 3, 2023 |
| Priority date | — |
| Expiry date | Jun 22, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16C20/60
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a method for discovering specific functional antibodies, in particular to a method for discovering specific functional antibodies based on sequence composition and frequency analysis of variable regions of immune host antibodies. Compared with conventional high-throughput antibody sequencing method, this method can quickly and accurately obtain the full-length sequence of the variable region of antibody containing candidate CDR3, the success rate of antibody gene pairing is high and it is suitable for the detection of few samples, and improves the efficiency of obtaining specific functional antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.