Method of sample preparation for maldi and automated system therefor
US11774332B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | May 18, 2022 |
| Grant date | Oct 3, 2023 |
| Priority date | — |
| Expiry date | May 18, 2042 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/40
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for preparing a biological sample for testing by Maldi where such methods are selected based on sample parameters. Maldi scores are obtained for a range of sample parameters (e.g. McFarland, dispense volume and number of dispenses). From the data, sample preparation parameters can be selected for a biological sample being prepared for Maldi testing. One sample preparation strategy uses multiple dispenses of sample with an intervening drying step, which yields more accurate Maldi scores, particularly for samples at the low range of McFarland values (e.g. below about 2).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.