CRISPR/Cas dropout screening platform to reveal genetic vulnerabilities associated with tau aggregation
US11781131B2 · kind B2 · utility
4Cited by
3References
36Claims
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Key dates
| Filing date | Mar 17, 2020 |
| Grant date | Oct 10, 2023 |
| Priority date | — |
| Expiry date | Feb 5, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6441
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Cas-protein-ready tau bio sensor cells, CRISPR/Cas synergistic activation mediator (SAM)-ready tau biosensor cells, and methods of making and using such cells to screen for genetic vulnerability associated with tau aggregation are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.