Microarray based multiplex pathogen analysis and uses thereof
US11781133B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Jun 30, 2022 |
| Grant date | Oct 10, 2023 |
| Priority date | — |
| Expiry date | Jun 30, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6895
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided herein is a method for manufacturing a microarray system, for example, 3-dimensional lattice microarray system, for DNA sequence detection and analysis. A solid support, such as a plastic substrate, is contacted with a formulation containing a plurality of nucleic acid probes, a plurality of bifunctional polymer linkers, such as oligothymidine linkers, and a solvent mixture of water and a water-miscible liquid. The bifunctional polymer linkers are attached to the solid support and the water is evaporated. Then the nucleic acid probes are attached to the bifunctional polymer linker.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.