FN3 domain-siRNA conjugates and uses thereof

US11781138B2 · kind B2 · utility

Assignee

• ARO Biotherapeutics Company · US

Inventors

• Russell C. Addis · Philadelphia, US
• Zhanna Druzina · Philadelphia, US
• Robert Kolakowski · Philadelphia, US
• Swapnil Kulkarni · Philadelphia, US
• Steven G. Nadler · Princeton, US
• Karyn O'Neil · Spring House, US
• Yao Xin · Philadelphia, US

Key dates

• Filing date: Oct 14, 2020
• Grant date: Oct 10, 2023
• Expiry date: Mar 31, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2320/32
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, as well as methods of making and using the molecules.