Patent · US Active

Modified biotin-binding proteins for immobilization

US11781177B2 · kind B2 · utility

0Cited by

23References

22Claims

0Family size

Assignee

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. · US

Inventors

Satwik Kamtekar · Mountain View, US
Lubomir Sebo · Redwood City, US
Leewin Chern · Fremont, US
Thomas Linsky · Mountain View, US
Jeremiah Hanes · Woodside, US
Erik Miller · Seattle, US
Ying Yang · Timonium, US
Stephen Yue · Eugene, US

Key dates

Filing date	Apr 6, 2020
Grant date	Oct 10, 2023
Priority date	—
Expiry date	Nov 27, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2537/143
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Compositions comprising covalently modified and mutated biotin-binding proteins, particularly biotin-binding proteins having a negative charge at physiological pH, are provided. Methods of producing such proteins are also provided, as are methods of immobilizing, sequencing, and making nucleic acids employing such proteins.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.