Patent · US Active

Formulation for inhibiting formation of 5-HT2B agonists and methods of using same

US11786487B2 · kind B2 · utility

2Cited by
65References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 19, 2021
Grant dateOct 17, 2023
Priority date
Expiry dateJan 9, 2042

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Drug combinations and their use are disclosed. A first drug is administered in combination with a second drug. The first drug such as fenfluramine is characterized by the formation of a metabolite including 5-HT2B agonists such as norfenfluramine with known adverse side effects. The second drug is in the form of a CYP inhibitor such as cannabidiol which modulates the formation of metabolite down thereby making the first drug safer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.