Patent · US Active

Sacubitril calcium salts

US11786498B2 · kind B2 · utility

0Cited by

1References

12Claims

0Family size

Assignee

Novartis AG · CH

Inventors

David Hook · Rheinfelden, CH
Bin Hu · Mesa, US
Florian Karl Kleinbeck · Zürich, CH
Ulrich Meier · Wetzikon, CH
Sibylle Mueller · Frenkendorf, CH
Jean-Paul Mutz · Blotzheim, FR
Jan Schlomach · Basel, CH
Paul Allen Sutton · Parsippany, US
Liladhar Murlidhar Waykole · East Hanover, US
Bernhard Wietfeld · Weil am Rhein, DE

Key dates

Filing date	Jul 2, 2015
Grant date	Oct 17, 2023
Priority date	—
Expiry date	Jul 2, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/13
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to polymorphic forms of the calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester. The calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester is useful in the treatment of various conditions and disorders responsive to the inhibition of neutral endopeptidases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.