Patent · US Active

Pharmaceutical composition comprising rosuvastatin and ezetimibe and a preparation method thereof

US11786526B2 · kind B2 · utility

0Cited by

0References

15Claims

0Family size

Assignee

Sanofi · FR

Inventors

Alena Prokopova · Praha, CZ
Jaroslava Svobodova · Křenice, CZ
Ondrej Dammer · Hostivice, CZ
Petr Mikes · Liberec, CZ

Key dates

Filing date	Aug 31, 2017
Grant date	Oct 17, 2023
Priority date	—
Expiry date	Aug 31, 2037

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K31/397
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a pharmaceutical composition comprising the active ingredients rosuvastatin of formula I, with the systematic name (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid or its pharmaceutically acceptable salts, esters, hydrates or solvates, and ezetimibe of formula II, with the systematic name (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one or its pharmaceutically acceptable salts, esters, hydrates or solvates, as well as a preparation method of this pharmaceutical composition. The weight ratio of the layers is 1:2 to 2:1.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.