Rotavirus vaccines

US11786590B2 · kind B2 · utility

Assignee

• CureVac SE · DE

Inventors

• Susanne RAUCH · Tübingen, DE
• Benjamin PETSCH · Tübingen, DE

Key dates

• Filing date: Jul 7, 2022
• Grant date: Oct 17, 2023
• Expiry date: Jul 7, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2720/12334
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides mRNA sequences comprising at least one coding region, encoding for at least one epitope of a protein, or of a fragment, variant or derivative thereof, of a virus of the genus rotavirus. Particularly preferred is the protein respectively the protein cleavage product VP8* of rotavirus. The mRNA sequence may be used as a vaccine or generally as a pharmaceutical composition for prophylaxis or treatment of rotavirus infections.