CD33 specific chimeric antigen receptors
US11787848B2 · kind B2 · utility
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45Claims
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Key dates
| Filing date | Jun 7, 2017 |
| Grant date | Oct 17, 2023 |
| Priority date | — |
| Expiry date | May 13, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are chimeric antigen receptors (CARs) for cancer therapy, and more particularly, CARs containing a scFv from a CD33 monoclonal antibody. Provided are immune effector cells containing such CARs, and methods of treating proliferative disorders such as acute myeloid leukemia (AML), and relapsed or refractory AML.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.