Rheologically biomimetic fluid surrogate
US11788044B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Mar 16, 2020 |
| Grant date | Oct 17, 2023 |
| Priority date | — |
| Expiry date | Jan 16, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/25
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention contemplates compositions, devices and methods of simulating biological fluids in a fluidic device, including but not limited to a microfluidic chip. In one embodiment, fluid comprising a colloid under flow in a microfluidic chip has a fluid density or viscosity similar to a bodily fluid, e.g. blood, lymph, lung fluid, or the like. In one embodiment, a fluid is provided as a Theologically biomimetic blood surrogate or substitute for simulating physiological shear stress and cell dynamics in fluidic device, including but not limited to immune cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.