Patent · US Active

Method of increasing proliferation of pancreatic beta cells, treatment method, and composition

US11788064B2 · kind B2 · utility

1Cited by

3References

13Claims

0Family size

Assignee

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · US

Inventors

Andrew F. Stewart · Pasadena, US
Courtney Ackeifi · New York, US
Peng Wang · Carlsbad, US
Bob Devita · New York, US

Key dates

Filing date	Jan 5, 2019
Grant date	Oct 17, 2023
Priority date	—
Expiry date	Jan 5, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2501/727
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are methods of increasing cell proliferation in a population of pancreatic beta cells. Also disclosed are methods of treating a subject for a condition associated with insufficient insulin secretion. Also disclosed is a composition comprising a DYRK1 A inhibitor and a GLP1R agonist. The disclosure further describes a method of regenerating pancreatic beta cells in a transplant patient.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.