Uridine diphosphate-dependent glycosyltransferase enzyme
US11788070B2 · kind B2 · utility
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4References
18Claims
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Key dates
| Filing date | Oct 6, 2021 |
| Grant date | Oct 17, 2023 |
| Priority date | — |
| Expiry date | Nov 18, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y204/01
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
In various aspects, the present invention provides uridine diphosphate-dependent glycosyltransferase (UGT) enzymes capable of catalyzing the transfer of a monosaccharide moiety from a NDP-sugar to the 3′ carbon of a sugar moiety of a substrate, such as a terpenoid glycan, thereby functioning as a “1-3 UGT.” In other aspects, the invention provides polynucleotides encoding the 1-3 UGT, and host cells comprising the same. In still other aspects, the invention provides methods for preparing glycosylated substrates, including steviol glycosides, using the enzyme and host cells of this disclosure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.