Nucleic acid sequencing using affinity reagents
US11788138B2 · kind B2 · utility
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47Claims
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Key dates
| Filing date | Oct 29, 2020 |
| Grant date | Oct 17, 2023 |
| Priority date | — |
| Expiry date | Jan 29, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/73
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorporation by binding to the reversible terminator a directly or indirectly labeled antibody or other affinity reagent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.