Glucose sensor electrode, preparation method therefor and use thereof

US11788984B2 · kind B2 · utility

Assignees

• South China University of Technology · CN
• GUANGDONG UNIVERSITY OF TECHNOLOGY · CN

Inventors

• Chengyun Ning · 流花街道, CN
• Zhen'gao Wang · 流花街道, CN
• Peng Yu · 东风镇, CN
• Lei Qian · Huizhou, CN
• Zhengnan Zhou · 流花街道, CN
• Jun Xing · Meekrap-oord, CN
• Junqi Chen · 流花街道, CN
• Lei Zhou · Tianjin, CN
• Guoxin Tan · 流花街道, CN

Key dates

• Filing date: Sep 21, 2018
• Grant date: Oct 17, 2023
• Expiry date: Apr 9, 2040

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N27/3271
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A glucose sensor electrode, a preparation method therefor and the use thereof are provided for the rapid and sensitive detection of glucose. The method involves: (1) performing an alkali heat treatment to form a nanoneedle-structured titanium dioxide on the surface of a titanium electrode; (2) forming micro-region grooves on a nanoneedle-structured titanium dioxide film layer to obtain a nanoneedle-structured titanium dioxide having a micropattern; (3) depositing a chlorine-doped polypyrrole in the grooves by using chronopotentiometry; (4) forming a nanocone-structured citric-acid-doped polypyrrole on the chlorine-doped polypyrrole by using chronopotentiometry; and (5) grafting an enzyme capable of detecting glucose to obtain the glucose sensor electrode. This simple and stable process is low in cost, efficiently grafts the enzyme capable of detecting glucose on the surface of the electrode, and provides a stable electrode with higher reliability for detecting glucose.