Nano-armored single cell product for treating Parkinson's disease through bacteria and a preparation method thereof
US11793840B2 · kind B2 · utility
0Cited by
1References
1Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 18, 2021 |
| Grant date | Oct 24, 2023 |
| Priority date | — |
| Expiry date | Oct 31, 2041 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a nano-armored single cell product, comprising a liposome and probiotics encapsulated by the liposome, wherein the probiotics are fermented to produce gamma-aminobutyric acid (GABA) that alleviates the activation of an inflammatory response in substantia nigra inducedin a MPTP induced PD model, thus mitigating an inflammatory injury to dopaminergic neurons in substantia nigra and having a neuroprotective effect; encapsulation of the probiotics by the liposome can protect the probiotics from strong acids and digestive enzymes in gastric acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.