Functionalized microbubble embodiments for ultrasound-mediated treatment and methods of making and using the same
US11793863B2 · kind B2 · utility
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22Claims
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Key dates
| Filing date | Apr 24, 2020 |
| Grant date | Oct 24, 2023 |
| Priority date | — |
| Expiry date | Nov 5, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are embodiments of a functionalized microbubble designed for treating and/or preventing vascular obstructions, including microvascular obstructions. The functionalized microbubble embodiments comprise a microbubble that can be activated upon exposure to ultrasound and further that has a lipid-based shell that is attached to an exteriorly-attached therapeutically active agent, such as a thrombolytic agent. Also disclosed herein are embodiments of a method for making and using the functionalized microbubble embodiments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.