Patent · US Active

Fusion protein composition(s) comprising masked type I interferons (IFNA and IFNB) for use in the treatment of cancer and methods thereof

US11795198B2 · kind B2 · utility

0Cited by
15References
27Claims
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Assignee

Inventors

Key dates

Filing dateSep 2, 2021
Grant dateOct 24, 2023
Priority date
Expiry dateSep 2, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/74
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Fusion Protein compositions comprising masked IFNs and methods of making masked IFNs are disclosed herein. Consequently, the masked IFNs can be fused to a Mab or binding fragment thereof and be administered to patients as a therapeutic modality and provide a method of treating cancer, immunological disorders and other disease.

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