Self-assembled nanoplatelet-enzyme bioconjugates providing for increased biocatalytic efficiency

US11795483B2 · kind B2 · utility

Assignee

• The Government of the United States of America, as represented by the Secretary of the Navy · US

Inventors

• Igor L. Medintz · Springfield, US
• Joyce Breger · Greenbelt, US
• Scott Walper · Springfield, US
• Michael H. Stewart · Springfield, US

Key dates

• Filing date: Jun 11, 2019
• Grant date: Oct 24, 2023
• Expiry date: Jan 17, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y503/01009
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A nanoplatelet serves as a substrate for immobilizing enzymes involved in consecutive reactions as a cascade. This results in a significant increase in the rate of catalysis as well as final product yield compared to non-immobilized enzymes or enzymes immobilized to quantum dots.