Methods for assessing cell surface glycosylation
US11796534B2 · kind B2 · utility
1Cited by
22References
28Claims
0Family size
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Key dates
| Filing date | Apr 13, 2018 |
| Grant date | Oct 24, 2023 |
| Priority date | — |
| Expiry date | Jun 23, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2570/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are methods for assessing cell surface glycans, e.g., N-glycans, by assessing a sample of released surface glycans, and determining the presence, absence, or level of glycans present in the sample. Also provided are methods of assaying and/or evaluating a cell composition by assessing the cell surface glycan profile of the cell composition and comparing the profile to a reference sample. Methods for manufacturing and/or culturing a plurality of cell compositions having consistent surface glycan expression with low variability are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.