Patent · US Active

CD8 T cell subsets as a biomarker for predicting non-fusion after spinal fusion surgery

US11802873B2 · kind B2 · utility

0Cited by

1References

7Claims

0Family size

Assignee

CHARITÉ—UNIVERSITÄTSMEDIZIN BERLIN · DE

Inventors

Simon REINKE · Berlin, DE
Sven GEISSLER · Berlin, DE
Georg Duda · Berlin, DE
Hans-Dieter Volk · Berlin, DE
Michael Fuchs · Boise, US
Katharina SCHMIDT-BLEEK · Berlin, DE
Patrick Strube · Jena, DE
Matthias Pumberger · Berlin, DE

Key dates

Filing date	May 29, 2018
Grant date	Oct 31, 2023
Priority date	—
Expiry date	Jun 15, 2040

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/52
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein is a method for predicting the probability of having or developing a non-fusion, wherein said method comprises determining the frequency of a subpopulation of CD8+ T cells selected from CD8+CD57+, CD8+CD28− and CD8+CD57+CD28− in a sample obtained from a patient. Also provided herein is a system for predicting the probability of having or developing a non-fusion.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.