Patent · US Active

Nucleic acid-binding photoprobes and uses thereof

US11807623B2 · kind B2 · utility

0Cited by
23References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 30, 2018
Grant dateNov 7, 2023
Priority date
Expiry dateJun 12, 2042

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/5008
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to photoactivatable compounds and methods of use thereof for determining binding site and other structural information about RNA transcripts. The invention also provides methods of identifying RNA transcripts that bind compounds and are thus druggable, methods of screening drug candidates, and methods of determining drug binding sites and/or accessible or reactive sites on a target RNA.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.