Patent · US Active

Detection and quantification of glycosylated peptides

US11807665B2 · kind B2 · utility

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20Claims

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Assignee

REGENERON PHARMACEUTICALS, INC. · US

Inventors

Avraham Z. Rosenberg · Holon, IL
Biao Shen · Longbeilingcun, CN

Key dates

Filing date	Jul 12, 2019
Grant date	Nov 7, 2023
Priority date	—
Expiry date	Aug 15, 2041

Classification

Technology area (CPC G)Physics
CPC primaryG01N2440/38
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

A method of purification and/or separation of glycopeptides and quantitation of same. The method includes contacting a sample comprising glycopeptides to a hydrophilic enrichment substrate under conditions that permit the glycopeptides to bind to the hydrophilic enrichment substrate. The glycopeptides are eluted from the hydrophilic enrichment substrate with an ammonium formate and acetonitrile (ACN) in water solution to create an enriched glycopeptide sample, which may be subjected to analysis to identify specific glycopeptides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.