Patent · US Active

Peroxisome biomarkers in HIV disease progression and peroxisome activating drugs for HIV treatment

US11807906B2 · kind B2 · utility

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4Claims
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Inventors

Key dates

Filing dateMay 7, 2018
Grant dateNov 7, 2023
Priority date—
Expiry dateSep 12, 2039

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/50
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present disclosure provides methods for assessing likelihood of development of HIV-associated neurocognitive disorder (HAND) in a HIV patient. Also provided herein are methods for treating a HIV patient, such as, a HIV patient with increased level of a mi RNA that downregulates a peroxin and/or decreased level of a peroxisomal activity biomarker and/or increased level of a substrate of a peroxisomal enzyme. The present disclosure also provides methods for monitoring efficacy of a treatment regimen for a HIV patient.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.