Patent · US Active

Injectable scaffold for treatment of intracranial aneurysms and related technology

US11813282B2 · kind B2 · utility

4Cited by
51References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 31, 2019
Grant dateNov 14, 2023
Priority date
Expiry dateJun 19, 2041

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61M2210/0687
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method for treating an aneurysm in accordance with a particular embodiment of the present technology includes intravascularly delivering a mixture including a biopolymer (e.g., chitosan) and a chemical crosslinking agent (e.g., genipin) to an aneurysm. The method further includes mixing the biopolymer and the chemical crosslinking agent to initiate chemical crosslinking of the biopolymer. The mixture is delivered to the aneurysm via a lumen and an exit port of a catheter while the chemical crosslinking is ongoing. The mixture exits the catheter as a single cohesive strand that at least partially agglomerates to form a mass occupying at least 75% of a total internal volume of the aneurysm. During delivery of the mixture, the method includes expanding a tubular flow diverter to reinforce a neck of the aneurysm.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.