Systems and methods for histotripsy immunosensitization
US11813485B2 · kind B2 · utility
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366References
25Claims
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Key dates
| Filing date | Jan 28, 2021 |
| Grant date | Nov 14, 2023 |
| Priority date | — |
| Expiry date | Jul 11, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2007/0039
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Systems and methods for histotripsy and immunotherapy are provided. In some embodiments, histotripsy can be applied to a target tissue volume to lyse and solubilize the target tissue volume to release tumor antigens. In some embodiments, an immune response of the treatment can be evaluated. In other embodiments, an immune therapy can be applied after applying the histotripsy. In one embodiment, the lysed and solubilized cells can be extracted from the tissue. The extracted cells can be used to create immune therapies, including vaccines.
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