Patent · US Active

Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators

US11814338B2 · kind B2 · utility

0Cited by

61References

37Claims

0Family size

Assignee

REATA PHARMACEUTICALS HOLDINGS, LLC · US

Inventors

Eric Anderson · Cleveland, US
Gary L. Bolton · Ann Arbor, US
Bradley W. Caprathe · Redford, US
Xin Jiang · Coppell, US
Chitase Lee · Ann Arbor, US
William H. Roark · Ann Arbor, US
Melean Visnick · Irving, US

Key dates

Filing date	Dec 6, 2021
Grant date	Nov 14, 2023
Priority date	—
Expiry date	Dec 6, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Disclosed herein are novel antioxidant inflammation modulators, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds and compositions thereof are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.