Patent · US Active

Sesquiterpenoid analogs

US11814396B2 · kind B2 · utility

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2Claims
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Key dates

Filing dateMay 3, 2021
Grant dateNov 14, 2023
Priority date
Expiry dateOct 4, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D493/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging drugs for cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.