Anti-CD25 for tumour specific cell depletion
US11814434B2 · kind B2 · utility
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5References
26Claims
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Key dates
| Filing date | Mar 13, 2019 |
| Grant date | Nov 14, 2023 |
| Priority date | — |
| Expiry date | Dec 28, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2015/8518
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides antibody sequences found in antibodies that bind to human CD25, in particular an anti CD25-a-672 antibody which do not block the binding of CD25 to IL-2 or IL-2 signalling. The claimed antibody binds to the epitopes: PHATFKAMA YKEGTM (42-56) and YQCVQGYRALH (150-160) on CD25. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical compositions and methods of treatment, in particular for treating cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.