Methods for treating and preventing neutrophil-derived net toxicity and thrombosis
US11819540B2 · kind B2 · utility
0Cited by
8References
30Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 2, 2020 |
| Grant date | Nov 21, 2023 |
| Priority date | — |
| Expiry date | Sep 23, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Embodiments of the technology described herein are based upon the discoveries that neutrophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.