Patent · US Active

ASGPR-binding compounds for the degradation of extracellular proteins

US11819551B2 · kind B2 · utility

5Cited by
11References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 29, 2022
Grant dateNov 21, 2023
Priority date
Expiry dateJul 29, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/95
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds and compositions that have an asialoglycoprotein receptor (ASGPR) binding ligand bound to an extracellular protein binding ligand for the selective degradation of the target extracellular protein in vivo to treat disorders mediated by the extracellular protein are described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.