Bromophenol-pyrazoline compound and synthesis method and use thereof
US11820763B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Jul 14, 2021 |
| Grant date | Nov 21, 2023 |
| Priority date | — |
| Expiry date | Jul 14, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D231/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a compound, and in particular to a bromophenol-pyrazoline compound and a synthesis method and use thereof. The bromophenol-pyrazoline compound is represented by a general structural formula below:The bromophenol-pyrazoline compound provided in the present invention has efficient inhibitory activity against the main protease Mpro, and interferes with the replication of coronavirus in cells, indicating that the compound has the effect of treating coronavirus pneumonia and thus has a broad prospect of application in the preparation of drugs for treating coronavirus pneumonia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.