Immunoglobulin fusion proteins and uses thereof
US11820807B2 · kind B2 · utility
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10References
4Claims
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Key dates
| Filing date | Jun 9, 2016 |
| Grant date | Nov 21, 2023 |
| Priority date | — |
| Expiry date | Jun 9, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/644
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is a single chain Fc. The amino acids in the hinge of the Fc is mutated, substituted, or deleted so that the hinge of Fc cannot form disulfide bonds. Methods for producing and using the fusion protein of the invention are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.