Phage-derived particles for in situ delivery of DNA payload into C. acnes population
US11820989B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Nov 4, 2021 |
| Grant date | Nov 21, 2023 |
| Priority date | — |
| Expiry date | Nov 18, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B40/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to C. acnes carrying DNA vectors with a C. acnes phage packaging signal and a gene of interest. The invention encompasses a C. acnes producer cell carrying DNA vectors, with a C. acnes phage packaging signal and a gene of interest, for the production of phage-derived particles that can robustly transduce C. acnes receiver cell allowing transgene expression. The invention encompasses C. acnes phage-derived particles carrying these vectors, C. acnes containing these vectors or modified by transduction of these phage-derived particles, and methods of using these phage-derived particles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.