System and method for classification of tissue based on Raman and fluorescence in high-wavenumber Raman spectrum
US11821841B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 7, 2022 |
| Grant date | Nov 21, 2023 |
| Priority date | — |
| Expiry date | Mar 7, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6419
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and system for classifying a tissue specimen is provided. The method includes: a) interrogating a tissue specimen with a first interrogation light; b) detecting first light from the tissue specimen resulting from the interrogation, wherein the first light includes a first scattered light component and a first fluorescence light component, and producing first signals; c) interrogating the tissue specimen with a second interrogation light at a second excitation wavelength, wherein the first and second excitation wavelengths are within about 2 nm of each other; d) detecting second light from the tissue specimen resulting from the interrogation, wherein the second light includes a second scattered light component and a second fluorescence light component, and producing second signals; e) determining a difference between the first and second lights; f) determining a fluorescence spectrum produced by the interrogation of the tissue specimen; and g) classifying the tissue specimen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.