Patent · US Active

System and method for detecting structural change of a molecule or its environment with NMR spectroscopy

US11821863B2 · kind B2 · utility

0Cited by

0References

20Claims

0Family size

Assignee

Bruker Biospin GmbH · DE

Inventors

Christian Fischer · Waldbronn, DE
Michael Bernstein · Livingston, US
Michael Fey · Andover, US
Ian Michael Clegg · Middlewich, GB

Key dates

Filing date	Jan 29, 2021
Grant date	Nov 21, 2023
Priority date	—
Expiry date	Jan 22, 2042

Classification

Technology area (CPC G)Physics
CPC primaryG01R33/465
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A system, method and computer program product for detecting indicators for structural changes of NMR active test molecules in a test sample, or indicators for structural changes of the environment of said test molecules in relation to a reference molecule. Initial local similarity values are obtained, using a similarity function and representing a local similarity between a reference spectrum and a test spectrum within corresponding similarity regions (SRR, SRT). The initial local similarity values represent a similarity map (SM1) in which contours of a first shape type are indicators (I1) for structural changes of the test molecule, and in which contours of a second shape type are indicators (I2) for structural changes of the environment of said test molecule in relation to the reference molecule.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.