Patent · US Active

Antimicrobial peptide ID13, preparation method and use thereof

US11827677B2 · kind B2 · utility

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1References

1Claims

0Family size

Assignee

Feed Research Institute, Chinese Academy of Agricultural Sciences · CN

Inventors

Jianhua Wang · Novi, US
Bing Li · Beijing, CN
Da Teng · Tangxia, CN
Ruoyu Mao · Beijing, CN
Xiumin Wang · Beijing, CN
Ya Hao · Beijing, CN
Na Yang · Beijing, CN

Key dates

Filing date	Oct 23, 2020
Grant date	Nov 28, 2023
Priority date	—
Expiry date	Aug 28, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/50
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention provides an antimicrobial peptide ID13 (with a sequence set forth in SEQ ID NO. 1), a preparation method and use thereof. The antimicrobial peptide ID3 is successfully expressed in Pichia pastoris using genetic engineering technology. The antimicrobial peptide ID13 of the present invention has an excellent bactericidal activity against Gram-positive bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus suis, and has a low hemolytic activity against mouse red blood cells and a low murine macrophage cytotoxicity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.