Method of quantitating unbound C5a in a sample
US11828683B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Oct 19, 2017 |
| Grant date | Nov 28, 2023 |
| Priority date | — |
| Expiry date | Sep 27, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/54366
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of quantitating free (unbound) human C5a complement protein (C5a) from a sample comprising: binding biotinylated anti-C5a capture antibody to strepavidin-coated particles; capturing the free (unbound) C5 in the sample; detecting the captured free C5a; and quantitating the captured free C5 using laser-induced fluorescence detection; wherein the method is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument; wherein human C5 is first removed from the sample.
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