Adipocyte-targeting DNA nanodrug and preparation and uses thereof
US11833207B2 · kind B2 · utility
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Key dates
| Filing date | Dec 22, 2020 |
| Grant date | Dec 5, 2023 |
| Priority date | — |
| Expiry date | Sep 6, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An adipocyte-targeting DNA nanodrug, and preparation and uses thereof. The drug is composed of an adipocyte-targeting DNA microstructure and tannic acid (TA) in a weight ratio of 1:25-30. Among them, the small molecular antioxidant TA is loaded into the DNA microstructure. The DNA microstructure incorporated with an adipocyte-targeting aptamer sequence can specifically recognize and bind with adipocytes. TA and DNA microstructure can interact with each other through multiple hydrogen bonds to form the adipocyte-targeting, safe and efficient DNA nanodrug.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.