Preparation method of pyrimidinylthio-benzoate oxime ester compound and application thereof as herbicide
US11834420B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 26, 2020 |
| Grant date | Dec 5, 2023 |
| Priority date | — |
| Expiry date | Jul 1, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01P13/00
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
A preparation method of a pyrimidinylthio-benzoate oxime ester compound and an application thereof are provided. The chemical structural formula of the pyrimidinylthio-benzoate compound is shown in the following formula (1). The preparation method includes step A: preparation of a substituted acetophenone oxime: taking hydroxylamine hydrochloride and a substituted acetophenone as a raw material, adding an alcohol as a solvent, and performing a reaction at 0° C.-80° C. for 1-5 hours under an alkaline condition to obtain the substituted acetophenone oxime; and step B: preparation of the compound: using 2-chloro-6-((4,6-dimethoxypyrimidin-2-yl)thio)benzoic acid and the substituted acetophenone oxime as a raw material, and performing a reaction under an action of an organic solvent, a dehydrating agent and a catalyst at 25° C. for 6-24 hours; after the reaction is completed, performing a suction filtration, and subjecting the filtrate to a decompression distillation and a recrystallization to obtain the compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.