Patent · US Active

Human IL-10 receptor alpha fusion proteins

US11834492B2 · kind B2 · utility

1Cited by

9References

11Claims

0Family size

Assignee

EPICENTRX, INC. · US

Inventors

Christopher Larson · San Diego, US
Tony Reid · San Diego, US
Bryan T. Oronsky · Los Altos Hills, US

Key dates

Filing date	Sep 27, 2018
Grant date	Dec 5, 2023
Priority date	—
Expiry date	Dec 22, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/50
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided is a fusion protein, e.g., a cytokine receptor fusion protein, e.g., an IL-10 trap, with a novel linker sequence to permit the fusion protein to functionally optimally, e.g., to permit a cytokine receptor portion of a cytokine receptor fusion protein to bind optimally to its target cytokine. The fusion protein, or an expression vector encoding for the fusion proteins, can be used to treat cell proliferative diseases and disorders, including certain forms of cancer and inflammatory disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.