Patent · US Active

Human induced pluripotent stem cell lines for modeling Alzheimer's disease and usage thereof

US11834648B2 · kind B2 · utility

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0References

13Claims

0Family size

Assignee

Shenzhen Cell Inspire Biotechnology Co., Ltd. · CN

Inventors

Yubo Yan · Lo Wu, CN
Jian-Ming Fu · Taichung, TW
Min Zhou · Suzhou, CN
Yuqing Liu · Hangzhou City, CN
Lixiang Jiang · Lo Wu, CN
Bo Yang · Zhejiang, CN
Jiayin YANG · Nanhu, CN

Key dates

Filing date	Nov 6, 2017
Grant date	Dec 5, 2023
Priority date	—
Expiry date	Apr 19, 2039

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/2821
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A method of generating a cellular model of Alzheimer's disease (AD) comprises integrating AD related gene to hiPSC to induce increased beta secretase and/or Abeta 42 peptides, and the cellular model of Alzheimer's disease (AD) is prepared by the method.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.