Drug composition and coating
US11839698B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 13, 2014 |
| Grant date | Dec 12, 2023 |
| Priority date | — |
| Expiry date | Mar 13, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2420/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
According to the invention there is provided inter alia a medical device for delivering a therapeutic agent to a tissue, the device having a solid surfactant-free particulate coating layer applied to a surface of the device, the coating layer comprising a therapeutic agent and at least one non-polymeric organic additive which is hydrolytically stable; wherein at least a proportion of the particulate coating layer comprising the therapeutic agent and the at least one organic additive melts as a single phase at a lower temperature than the melting point of the therapeutic agent and the at least one organic additive when in pure form; wherein the therapeutic agent is paclitaxel; and wherein the therapeutic agent, when formulated in the coating layer, is stable to sterilization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.