Method for applying thermal energy to a receptacle and detecting an emission signal from the receptacle
US11840727B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 22, 2020 |
| Grant date | Dec 12, 2023 |
| Priority date | — |
| Expiry date | Mar 20, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6484
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Multiple receptacles containing a reaction mixture are transported to corresponding receptacle wells of a thermally-conductive receptacle holder in thermal communication with a support that is in thermal communication with a heat sink. The heat sink is pre-heated to a temperature above ambient temperature, and the temperature of the receptacle holder is cycled. Optical communication is established between each of the receptacle wells and an excitation signal source and an emission signal detector during cycling, and whether an emission signal is emitted from any of the receptacles is determined as an indication of the presence of a target nucleic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.