Patent · US Active

Method and device for estimating a STED resolution

US11841324B2 · kind B2 · utility

0Cited by
8References
16Claims
0Family size

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Key dates

Filing dateMar 25, 2021
Grant dateDec 12, 2023
Priority date
Expiry dateMay 28, 2042

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG06T2207/30168
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method for estimating a stimulated emission depletion microscopy (STED) resolution includes generating a first frame representing a reference image from a field-of-view, the reference image having a predetermined reference resolution, and generating at least one second frame representing a STED image from the same field-of-view, the STED image having the STED resolution to be estimated. The at least one second frame is blurred by applying a convolution kernel with at least one fit parameter to the second frame. An optimal value of the at least one fit parameter of the convolution kernel is determined for which a difference between the first frame and the blurred at least one second frame is minimized. The STED resolution is estimated based on the optimal value of the at least one fit parameter and the predetermined reference resolution.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.